We have to understand that the process of blood vessel dilation has an effect in a range of results in the muscles, for instance low blood pressure (different than less diameter of blood vessels), thermoregulation, between others, as well as allowing a higher absorption of nutritional substances to the muscle location all over the blood, in accordance with the requirements. Therefore, a few physiological systems might not function as exactly as achievable, and in a few cases just can not fulfill the requirements which we want. As a result, there are a few physiological aspects or not so much mechanical aspects to get a higher level of vasodilation.
Exemestane is often combined with tamoxifen during PCT. Doing so allows for an enhanced anti-estrogenic effect when both the enzyme (exemestane) and receptor (tamoxifen) sites are blocked. The added advantage of using exemestane over other aromatase inhibitors is that the aromatase enzyme stays deactivated long after the PCT protocol finishes. This prevents estrogenic activity from resuming immediately and thus causing estrogenic side-effects again. Instead the aromatase enzymes will slowly return to normal function. The addition of tamoxifen also has a positive effect on cholesterol.