Studies indicate that Advair HFA is as effective as Advair Diskus. 2 Advair HFA was studied in four high-quality studies of 1,517 adults and adolescents. The people in this study were using a range of medications, from as-needed inhalers to daily inhaled corticosteroids or LABAs before the study started. Lung function improved more with Advair HFA (45/21 and 115/21 doses) than fluticasone alone, salmeterol alone, or placebo. People treated with Advair HFA had fewer asthma symptoms and used less rescue medication. A head-to-head comparison showed that Advair HFA 230/21 is as effective as Advair Diskus 500/50, and both are more effective than fluticasone alone.
Fluticasone nasal spray controls the symptoms of hay fever or allergies but does not cure these conditions. Your symptoms will probably not begin to improve for at least 12 hours after you first use fluticasone, but it may take several days or longer before you feel the full benefit of fluticasone. Fluticasone works best when used regularly. Use fluticasone on a regular schedule unless your doctor has told you to use it as needed. Call your doctor if your symptoms get worse or do not improve after you use nonprescription fluticasone nasal spray daily for 1 week.