Flovent HFA comes as an inhaler with a separate metal canister containing the medication. 2 Do not use the Flovent inhaler with other medications. Do not use other inhalers with the Flovent canister. Clean your Flovent inhaler once per week. 4 Use a clean, damp cotton swap to clean the small opening where the medicine sprays out. Wipe the mouthpiece with a damp, clean tissue and allow the inhaler to air dry. Throw away the canister and inhaler when the counter reads 000. You have used all the medication. Store your Flovent HFA at room temperature (68˚F and 77˚F). Avoid high heat or flames.
Studies indicate that Advair HFA is as effective as Advair Diskus. 2 Advair HFA was studied in four high-quality studies of 1,517 adults and adolescents. The people in this study were using a range of medications, from as-needed inhalers to daily inhaled corticosteroids or LABAs before the study started. Lung function improved more with Advair HFA (45/21 and 115/21 doses) than fluticasone alone, salmeterol alone, or placebo. People treated with Advair HFA had fewer asthma symptoms and used less rescue medication. A head-to-head comparison showed that Advair HFA 230/21 is as effective as Advair Diskus 500/50, and both are more effective than fluticasone alone.
Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen , estrogen , or mineralocorticoid receptors , thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (. mast cell , eosinophil , neutrophil , macrophages , and lymphocytes ) and mediators (. histamine , eicosanoids , leukotrienes , and cytokines ) involved in inflammation . Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability .